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Variability in methotrexate serum and cerebrospinal fluid pharmacokinetics in children with acute lymphocytic leukemia: relation to assay methodology and physiological variables

Hematological MalignancyPediatric HematologyMixed-phenotype Acute LeukemiaMalignant Blood DisorderHematologyPediatricsLaboratory MedicineClinical ChemistryPhysiological VariablesCerebrospinal Fluid PharmacokineticsMedicineMethotrexate Serum