Concepedia

Publication | Closed Access

Stimulation of Soluble Guanylate Cyclase Prevents Cigarette Smoke–induced Pulmonary Hypertension and Emphysema

DOI

92

Citations

41

References

2014

Year

Borja Lobo, Alexandra Pichl, Nirmal Parajuli, Michael Seimetz, Raquel Puig-Pey, Elisabet Ferrer, Víctor I. Peinado, David Domínguez‐Fandos, Athanasios Fysikopoulos, Johannes‐Peter Stasch,
American Journal of Respiratory and Critical Care Medicine

Abstract

The sGC-cGMP axis is perturbed by chronic exposure to CS. Treatment of COPD animal models with sGC stimulators can prevent CS-induced PH and emphysema.

References

YearCitations

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