The discovery of high affinity agonists of GPR109a with reduced serum shift and improved ADME properties - Concepedia

Concepedia

Publication | Open Access

The discovery of high affinity agonists of GPR109a with reduced serum shift and improved ADME properties

DOI Full Paper Access

15

Citations

8

References

2010

Year

Jason E. Imbriglio, Daniel A. DiRocco, Rena Bodner, Subharekha Raghavan, Wei‐Chun Chen, Daria M. Marley, Craig K. Esser, Tom G. Holt, Michael S. Wolff, Andrew K.P. Taggart,

Bioorganic & Medicinal Chemistry Letters

Signal TransductionBiochemistryReduced Serum ShiftMedicineG Protein-coupled ReceptorFunctional SelectivityReceptor (Biochemistry)High Affinity AgonistsNon-peptide LigandImproved Adme PropertiesPharmacologyDrug Discovery

References

	Year	Citations

Page 1

Page 1