Very early detection of <i>RET</i> proto‐oncogene mutation is crucial for preventive thyroidectomy in multiple endocrine neoplasia type 2 children

Abstract

The consistent finding of C-cell disease in all the juvenile carriers who underwent preventive thyroidectomy emphasizes the relevance of early screening in children at risk of developing MTC. The presence of MTC in the specimen of prophylactic thyroidectomy from a 17 month old girl highlights the importance of thyroidectomy as soon as the molecular diagnosis is confirmed.