Gene Expression Profiling of Nasal Polyps Associated With Chronic Sinusitis and Aspirin‐Sensitive Asthma

Abstract

Nasal polyps appear to have characteristic transcriptional signatures compared to normal sinonasal mucosa. The five genes identified in this study likely play roles in the pathogenesis of polyps associated with CRS and ASA, and are therefore attractive targets for novel medical therapies for these common debilitating diseases.