Clinical and Histologic Response of Subcutaneous Expanded Polytetrafluoroethylene (Gore-Tex) and Porous High-Density Polyethylene (Medpor) Implants to Acute and Early Infection

Abstract

Because of differences in pore size, PHDPE promotes faster fibrovascular ingrowth. The presence of vascularized host tissue in and around the implant lends stability and resistance to experimentally induced infection. Conservative management of clinical implant infections should be considered if bacterial seeding occurs after substantial fibrovascular ingrowth is present. Future alloplast designs should include pore sizes that will encourage invasion of the implant by host tissue.