Emerging infectious diseases · 2004 · 71 citations · 9 references
Public HealthInfectious Disease ControlInfectious DiseasesEpidemiologyInfectious Disease EpidemiologyOutbreak InvestigationCase DefinitionCase Reporting SystemsInfectious Disease DetectionOutbreak ManagementOutbreak ResponseRespiratory Infectious DiseasesCase-based ReportingDiagnostic TestingDisease Outbreak SurveillanceHospital Outbreak InvestigationNosocomial Respiratory InfectionsOutbreak CharacterizationReclassificationSevere Acute Respiratory Syndrome
We studied the severe acute respiratory syndrome (SARS) outbreak in Taiwan, using the daily case-reporting data from May 5 to June 4 to learn how it had spread so rapidly. Our results indicate that most SARS-infected persons had symptoms and were admitted before their infections were reclassified as probable cases. This finding could indicate efficient admission, slow reclassification process, or both. The high percentage of nosocomial infections in Taiwan suggests that infection from hospitalized patients with suspected, but not yet classified, cases is a major factor in the spread of disease. Delays in reclassification also contributed to the problem. Because accurate diagnostic testing for SARS is currently lacking, intervention measures aimed at more efficient diagnosis, isolation of suspected SARS patients, and reclassification procedures could greatly reduce the number of infections in future outbreaks.
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Transmission Dynamics and Control of Severe Acute Respiratory Syndrome
Marc Lipsitch, Ted Cohen, Ben S. Cooper et al. · Science · 2003 · 1.6K citations · Full text
Veterinary Medicine, Infectious Disease Control, Infectious Diseases +17