Radicals in the reaction between peroxynitrite and uric acid identified by electron spin resonance spectroscopy and liquid chromatography mass spectrometry

Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis.

B N Ames, Richard Cathcart, Elizabeth Schwiers et al. · Proceedings of the National Academy of Sciences · 1981 · 2.9K citations · Full text

Life Sciences, Biochemistry, Physiology +17

Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide

Willem H. Koppenol, Juan Moreno, William A. Pryor et al. · Chemical Research in Toxicology · 1992 · 1.3K citations

Life Sciences, Chemistry, Toxicology +10

Elevated Uric Acid Increases Blood Pressure in the Rat by a Novel Crystal-Independent Mechanism

Marilda Mazzali, Jeremy Hughes, Yoon-Goo Kim et al. · Hypertension · 2001 · 1.3K citations

Medicine, Nephrology, Pharmacology +10

Uric Acid: The Oxidant-Antioxidant Paradox

Yuri Y. Sautin, Richard J. Johnson · Nucleosides Nucleotides & Nucleic Acids · 2008 · 959 citations · Full text

Life Sciences, Cardiology, Physiology +16

Spin trapping

Edward G. Janzen · Accounts of Chemical Research · 1971 · 854 citations

Natural Sciences, Chemistry, Analytical Chemistry +5