Homeopathy · 2008 · 47 citations · 19 references
NursingPharmacologyPharmacotherapyClinical PharmacologyWomen's HealthWomen's Health PharmacotherapyMenopause CareMenopause ManagementMenopause PharmacotherapySide EffectsWomen's Health CareManaging Hot FlashesMenopausal StatusMenopausal Symptom ReliefMenopause Symptom ManagementObservational Study AnalysisObservational Study EvaluationObservational Study Evidence
OBJECTIVE: There is great controversy concerning treatment for menopausal symptoms. We evaluated homeopathic treatments for hot flushes and their effect on quality of life in menopausal women. METHODS: Open, multi-national prospective, pragmatic and non-comparative observational study of homeopathic treatments prescribed and their effectiveness, observing their impact on quality of life. RESULTS: Ninety-nine physicians in 8 countries took part in this study and included 438 patients with an average age of 55. Homeopathic medicines were prescribed to all patients; 98% of the prescription lines were for homeopathic medicines. Lachesis mutus, Belladonna, Sepia officinalis, Sulphur and Sanguinaria canadensis were the most prescribed. A non-homeopathic treatment and/or food supplement prescribed for 5% of the patients. This observational study revealed a significant reduction (p<0.001) in the frequency of hot flushes by day and night and a significant reduction in the daily discomfort they caused (mean fall of 3.6 and 3.8 points respectively, on a 10cm visual analogue scale; p<0.001). Ninety percent of the women reported disappearance or lessening of their symptoms, these changes mostly taking place within 15 days of starting homeopathic treatment. CONCLUSIONS: The results of this observational study suggest that homeopathic treatment for hot flushes in menopausal women is effective. Further studies including randomized controlled trials should be conducted.
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Breast cancer and hormone-replacement therapy in the Million Women Study
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Estrogen plus Progestin and the Risk of Coronary Heart Disease
JoAnn E. Manson, Judith Hsia, Karen Johnson et al. · New England Journal of Medicine · 2003 · 2.1K citations · Full text
Medicine, Cardiology, Endocrinology +12