High-pressure stopped-flow apparatus for the study of fast reactions in solution

Abstract

A high-pressure stopped-flow apparatus with spectrophotometric detection has been exploited, which enables one to follow fast reactions in various media at pressure up to 2000 kg cm−2. The rate of the following reactions was successfully measured at various pressures: (1) reaction of nickel (II) nitrate with 1-(2-pyridylazo)-2-naphthol in glacial acetic acid and (2) reaction of nickel (II) perchlorate with isoquinoline in N,N-dimethylformamide. The apparatus allows the measurement of activation volumes for reactions with half-lives longer than several milliseconds.