A New Approach for Adipose Tissue Regeneration Based on Human Mesenchymal Stem Cells in Contact to Hydrogels—an In Vitro Study

Abstract

In this study an approach for adipose tissue regeneration based on human mesenchymal stem cells and hydrogels as supporting matrix was evaluated. The gelatin-based hydrogels developed in this study were cytocompatible and stem cell adhesion onto hydrogel surfaces was higher as compared to tissue culture polystyrene. Furthermore, the adipogenic differentiation degree was increased. These results are promising for future applications of hydrogels in adipose tissue regeneration strategies.