An Unusual Lymphocytic Perivascular Infiltration in Tissues Around Contemporary Metal-on-Metal Joint Replacements

Abstract

The pattern and type of inflammation seen in periprosthetic tissues obtained from hips with metal-on-metal and metal-on-polyethylene implants are very different. At the present time, we do not know the prevalence or clinical implications of these histologic findings, but we suggest that they may represent a novel mode of failure for some metal-on-metal joint replacements.