Evaluation of antibacterial activity of crude extracts of ascidian Didemnum psammathodes Sluiter, 1895 against isolated human and fish pathogens

Abstract

To evaluate the antimicrobial activities of ascidian Didemnum psammathodes (D. psammathodes) against human and fish pathogenic organisms. In this study antimicrobial activities were carried out by standard disc diffusion method. In this experiment 40 human, fish bacterial and fungal pathogens were isolated and assayed against 7 different solvents such as methanol, acetone, ethanol, n-butanol, chloroform, ethyl acetate and dichloromethane. Each solvent were assayed at different concentrations of 25, 50, 75, 100 mg/mL. From this experiment solvent having higher concentrations showed high inhibition activity and the fungi are showed more resistant than the bacterial strains used. These results indicate that the ascidian D. psammathodes is found to have remarkable antimicrobial activities against isolated microbes. Further studies will fulfill for purification and structural elucidation of antimicrobial drugs.