Caveolin 1 mRNA is Overexpressed in Malignant Renal Tissue and Might Serve as a Novel Diagnostic Marker For Renal Cancer

Abstract

To our knowledge, this is the first study to show that CAV1 mRNA expression, using quantitative real-time PCR, is significantly higher in RCC compared with normal renal tissue and increases with tumor stage. CAV1 mRNA expression might serve as a candidate biomarker for objective prognosis indicating RCC aggressiveness. Our data encourage further investigations to determine the role of CAV1 in RCC.