The prevalence of 4G/5G polymorphism of plasminogen activator inhibitor-1 ( <i>PAI</i> -1) gene in central serous chorioretinopathy and its association with plasma PAI-1 levels

Abstract

Although our results demonstrated that the patients with acute CSCR have higher serum PAI-1 concentrations than the controls, no significant difference was found in the genotype disturbances of the PAI-1 gene between the groups. The current study indicates that 4 G/5 G polymorphism in the promoter of the PAI-1 gene cannot be considered a risk factor for the elevated serum PAI-1 levels and consequent development of CSCR.