Advanced glycation end products upregulate angiogenic and pro-inflammatory cytokine production in human monocyte/macrophages

Vascular endothelial growth factor (VEGF) and its receptors

Gera Neufeld, Tzafra Cohen, Stela Gengrinovitch et al. · The FASEB Journal · 1999 · 3.5K citations

Medicine, Cell Biology, Oncology +17

Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry

Matthias Wilm, Tony Houthaeve, Stephen Breit et al. · Nature · 1996 · 1.7K citations

Life Sciences, Biochemistry, Molecular Biology +15

Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes.

A.M. Schmidt, Osamu Hori, J X Chen et al. · Journal of Clinical Investigation · 1995 · 896 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

N ε-(Carboxymethyl)Lysine Adducts of Proteins Are Ligands for Receptor for Advanced Glycation End Products That Activate Cell Signaling Pathways and Modulate Gene Expression

Thomas Kislinger, Caifeng Fu, Birgit Huber et al. · Journal of Biological Chemistry · 1999 · 864 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Receptor for Advanced Glycation End Products (RAGE)-mediated Neurite Outgrowth and Activation of NF-κB Require the Cytoplasmic Domain of the Receptor but Different Downstream Signaling Pathways

Henri J. Huttunen, Carole Fages, Heikki Rauvala · Journal of Biological Chemistry · 1999 · 629 citations · Full text

Life Sciences, Cell Biology, Neuroscience +13