ELECTROCHEMICALLY INDUCED HEPATIC NECROSIS: THE NEXT STEP FORWARD IN PATIENTS WITH UNRESECTABLE LIVER TUMOURS?

Abstract

This study demonstrates that electrolysis-induced hepatic necrosis is produced without an increase in temperature; clearly cell death results from the direct effects of cytotoxic electrode products and an alteration of intracellular pH. Consequently, it is likely that as a method for ablating liver tumours, electrolysis should be associated with fewer complications than other forms of locoregional treatment.