Quantification of tapentadol in canine plasma by HPLC with spectrofluorimetric detection: Development and validation of a new methodology

Efficacy and safety of tapentadol extended release for the management of chronic low back pain: results of a prospective, randomized, double-blind, placebo- and active-controlled Phase III study

Robert Buynak, Douglas Y. Shapiro, Akiko Okamoto et al. · Expert Opinion on Pharmacotherapy · 2010 · 250 citations

Medicine, Pharmacotherapy, Clinical Pharmacology +16

Efficacy and Safety of Tapentadol Extended Release Compared with Oxycodone Controlled Release for the Management of Moderate to Severe Chronic Pain Related to Osteoarthritis of the Knee

Marc Afilalo, Mila Etropolski, Brigitte Kuperwasser et al. · Clinical Drug Investigation · 2010 · 227 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +11

Long-term Safety and Tolerability of Tapentadol Extended Release for the Management of Chronic Low Back Pain or Osteoarthritis Pain

James Wild, Stefan Grond, Brigitte Kuperwasser et al. · Pain Practice · 2010 · 181 citations

Medicine, Pharmacology, Pharmacotherapy +17

Efficacy and tolerability of tapentadol immediate release and oxycodone HCl immediate release in patients awaiting primary joint replacement surgery for end-stage joint disease: A 10-day, phase III, randomized, double-blind, active- and placebo-controlled study

Craig T. Hartrick, Ilse Van Hove, Jens‐Ulrich Stegmann et al. · Clinical Therapeutics · 2009 · 180 citations

Medicine, Orthopedic Surgery, Surgery +8

A randomized, double-blind, phase III study comparing multiple doses of tapentadol IR, oxycodone IR, and placebo for postoperative (bunionectomy) pain

Stephen E. Daniels, David Upmalis, Akiko Okamoto et al. · Current Medical Research and Opinion · 2009 · 142 citations

Medicine, Pharmacotherapy, Surgery +17