Human Heredity · 1970 · 77 citations · 0 references
Life SciencesGeneticsHuman GeneticsQuantitative GeneticsStatistical GeneticsGene MappingGenetic LinkageLinkage AnalysisLinkage DisequilibriumQuantitative Trait LociAssociation Between Linked Markers And TraitsGenetic Linkage Map ConstructionLinkage Analysis In Complex TraitsLinkage HeterogeneityLod Score CalculationMarker Segregation AnalysisMarker-based Linkage MappingRecombination Fraction Estimation
Lod scores for linkage of the albumin and Gc loci have been calculated for 21 pedigrees in which six different types of albumin variants are segregating. There is no evidence for heterogeneity in the linkage distance among the different types of variants. The most likely value for the recombination fraction in the combined data is at Ô = 0.023.