Concepedia

Facile Synthesis of Substituted N-Monoalkylaromatic Amines Under PTC Conditions

Uttam R. Kalkote, Anil Choudhary, A. A. NATU, Rajgopal J. Lahoti, N. R. AYYANGAR

Synthetic Communications · 1991 · 16 citations · 6 references

DOI

Concepts

Abstract

Abstract Substituted aromatic amides were alkylated under PTC conditions. Compounds with ortho electron withdrawing substituents furnished exclusively monoalkyl amines. A plausible mechanism has been suggested.

References

6

Dictionary of Organic Compounds

JOHN READ · Nature · 1943 · 1.1K citations

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The synthesis of isoquinolines, indoles and benzthiophen by an improved Pomeranz-Fritsch reaction, using boron trifluoride in trifluoroacetic anhydride

M.J. Bevis, E.J. Forbes, Nagaraja Naik et al. · Tetrahedron · 1971 · 46 citations

, , +10

The mechanism of N-alkylation of weak N-H-acids by phase transfer catalysis

Ekehard V. Dehmlow, Rainer Thieser, Hayder A. Zahalka et al. · Tetrahedron Letters · 1985 · 24 citations

, , +13

A Simple and Economical Method for the Alkylation of Benzanilides<sup>1</sup>

N. R. AYYANGAR, Anil Choudhary, Uttam R. Kalkote et al. · Synthetic Communications · 1988 · 23 citations

, , +14

Specific Phase-Transfer Catalyzed<i>N</i>-Monoalkylation of 2-Aminobenzophenones

Gilbert Mouzin, Henri Cousse, Jean-Marie Autin · Synthesis · 1981 · 13 citations

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