Chronic Open-Angle Glaucoma and Associated Ophthalmic Findings in Monozygotic Twins and Their Spouses in Iceland

Abstract

The statistically significant higher concordance of glaucoma--and the high correlation of mean IOP, mean axial length, anterior chamber depth, and refractive error--in twin pairs and the lack of association of these factors in twin/spouse pairs strongly suggests the importance of genetic factors for these ocular parameters.