STUDIES IN STEROID METABOLISM. XIX. THE a-KETOSTEROID EXCRETION PATTERN IN NORMAL MALES 1

Abstract

The urinary steroids afford a means for evalua- tion of the production of steroid hormones by the adrenal and gonads. Any alteration in either rate of type of hormone production by the glands re- sulting from specific disease or from hormonal therapy therefore must be manifest by qualitative or quantitative change in the excretion of steroid hormone metabolites. In order to delineate the composition of these metabolites in normal healthy subjects, the present investigation describing the a-ketosteroid excretion pattern was undertaken.