Greater potency of darbepoetin‐<b>α</b> than erythropoietin in suppression of serum hepcidin‐25 and utilization of iron for erythropoiesis in hemodialysis patients

Abstract

This study demonstrated that DPO-α has a greater advantage than rHuEPO in that it facilitates iron mobilization from body stores into bone marrow to induce effective erythropoiesis and thus could protect against possible harmful effects caused by excessive iron stores in the body.