Identification of Peptide Mimotopes of Trypanosoma brucei gambiense Variant Surface Glycoproteins

Liesbeth Carolien Van Nieuwenhove, Stijn Rogé, Fatima Balharbi, Tessa Dieltjens, Thierry Laurent, Yves Guisez, Philippe Büscher, Veerle Lejon

PLoS neglected tropical diseases · 2011 · 18 citations · 23 references

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Abstract

We successfully identified peptides that mimic epitopes on the native trypanosomal VSGs LiTat 1.5 and LiTat 1.3. These mimotopes might have potential for the diagnosis of human African trypanosomiasis but require further evaluation and testing with a large panel of HAT positive and negative sera.

References

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