Long-term intrathecal opioid therapy with a patient-activated, implanted delivery system for the treatment of refractory cancer pain

Pain Relief by Intrathecally Applied Morphine in Man

Josef K. Wang, Lee A. Nauss, Juergen E. Thomas · Anesthesiology · 1979 · 939 citations · Full text

Pain Disorders, Health Sciences, Pain Relief +15

Randomized Clinical Trial of an Implantable Drug Delivery System Compared With Comprehensive Medical Management for Refractory Cancer Pain: Impact on Pain, Drug-Related Toxicity, and Survival

Thomas J. Smith, Peter S. Staats, Timothy R. Deer et al. · Journal of Clinical Oncology · 2002 · 715 citations

Epidural clonidine analgesia for intractable cancer pain

James C. Eisenach, Stuart DuPen, Michel Y. Dubois et al. · Pain · 1995 · 537 citations

Pain Therapy, Surgical Oncology, Pain Medicine +18

Intraspinal morphine for chronic pain: A retrospective, multicenter study

Judith A. Paice, Richard D. Penn, Susan Shott · Journal of Pain and Symptom Management · 1996 · 297 citations · Full text

Pain Therapy, Health Sciences, Acute Pain +8

Continuous Low-Dose Intrathecal Morphine Administration in the Treatment of Chronic Pain of Malignant Origin

Burton M. Onofrio, Tony L. Yaksh, Phillip G. Arnold · Mayo Clinic Proceedings · 1981 · 234 citations