Epidermal Growth Factor Prevents Acetaldehyde‐Induced Paracellular Permeability in Caco‐2 Cell Monolayer

Abstract

These results indicate that EGF attenuates acetaldehyde-induced disruption of tight junctions and adherens junctions and prevents acetaldehyde-induced reorganization of actin cytoskeleton and its interaction with occludin, ZO-1, E-cadherin, and beta-catenin.