Simultaneous determination of 5-aminosalicylic acid and 5-acetylaminosalicylic acid by high-performance liquid chromatography

AN EXPERIMENT TO DETERMINE THE ACTIVE THERAPEUTIC MOIETY OF SULPHASALAZINE

A K Azad Khan, J Piris, S. C. Truelove · The Lancet · 1977 · 821 citations

Medicinal Chemistry, Pharmaceutical Science, Biochemistry +9

Effect of sulphapyridine, 5-aminosalicylic acid, and placebo in patients with idiopathic proctitis: a study to determine the active therapeutic moiety of sulphasalazine.

P A van Hees, J. Bakker, J H van Tongeren · Gut · 1980 · 322 citations · Full text

Active Therapeutic Moiety, Antibiotics, Gastrointestinal Pharmacology +10

TREATMENT OF ULCERATIVE COLITIS WITH HIGH-DOSE 5-AMINOSALICYLIC ACID ENEMAS

Massimo Campieri, Giorgio Assuero Lanfranchi, Gabriele Bazzocchi et al. · The Lancet · 1981 · 249 citations

Medicine, Surgery, Gastroenterology +1

5-Aminosalicylic Acid in a Slow-Release Preparation: Bioavailability, Plasma Level, and Excretion in Humans

Sten Nørby Rasmussen, S Bondesen, E Hvidberg et al. · Gastroenterology · 1982 · 225 citations

Health Sciences, Biochemistry, Gastrointestinal Pharmacology +8

Effect of sulphasalazine in patients with active Crohn's disease: a controlled double-blind study.

P A van Hees, H J van Lier, P H van Elteren et al. · Gut · 1981 · 152 citations · Full text

Inflammation, Inflammatory Activity, Functional Gastrointestinal Disorder +11