Elucidation of the Streptomyces coelicolor Pathway to 2-Undecylpyrrole, a Key Intermediate in Undecylprodiginine and Streptorubin B Biosynthesis

One-step inactivation of chromosomal genes in <i>Escherichia coli</i> K-12 using PCR products

Kirill A. Datsenko, Barry L. Wanner · Proceedings of the National Academy of Sciences · 2000 · 15.2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Gene disruption in Escherichia coli: TcR and KmR cassettes with the option of Flp-catalyzed excision of the antibiotic-resistance determinant

Peter Cherepanov, Wilfried Wackernagel · Gene · 1995 · 2K citations

Life Sciences, Genetics, Microbiology +17

PCR-targeted <i>Streptomyces</i> gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin

Bertolt Gust, Gregory L. Challis, Kay Fowler et al. · Proceedings of the National Academy of Sciences · 2003 · 1.4K citations

Life Sciences, Biotechnology, Microbiology +14

Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilizing a novel integration vector

Douglas J. MacNeil, Keith M. Gewain, Carolyn L. Ruby et al. · Gene · 1992 · 761 citations

Life Sciences, Biotechnology, Microbiology +9

Evidence that the Extracytoplasmic Function Sigma Factor ς ^E Is Required for Normal Cell Wall Structure in <i>Streptomyces coelicolor</i> A3(2)

Mark S. B. Paget, Leony Chamberlin, Abdelmadjid Atrih et al. · Journal of Bacteriology · 1999 · 415 citations · Full text

Life Sciences, Microbiology, Molecular Biology +13