Concepedia

Role of the transcriptional factor C/EBPβ in free fatty acid-elicited β-cell failure

Valérie Plaisance, Véronique Perret, Dimitri Favre, Amar Abderrahmani, Jiang-Yan Yang, Christian Widmann, Romano Regazzi

Molecular and Cellular Endocrinology · 2008 · 24 citations · 66 references

DOI

Concepts

References

66

β-Cell Deficit and Increased β-Cell Apoptosis in Humans With Type 2 Diabetes

Alexandra E. Butler, Juliette Janson, Susan Bonner‐Weir et al. · Diabetes · 2003 · 4K citations

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Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40

Yasuaki Itoh, Yuji Kawamata, Masataka Harada et al. · Nature · 2003 · 1.5K citations

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Fatty acid-induced β cell apoptosis: A link between obesity and diabetes

Michio Shimabukuro, Yan-Ting Zhou, Moshe Levi et al. · Proceedings of the National Academy of Sciences · 1998 · 1.1K citations · Full text

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Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle.

Yun Zhou, V. Grill · Journal of Clinical Investigation · 1994 · 687 citations · Full text

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Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients

Hiroyasu Sakuraba, Hiroki Mizukami, Nobuo Yagihashi et al. · Diabetologia · 2002 · 679 citations · Full text

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