Ginsenoside Rg1 Improves Male Copulatory Behavior Via Nitric Oxide/Cyclic Guanosine Monophosphate Pathway

Abstract

Ginsenoside Rg1 improved copulatory behavior of male mice and this may attribute to its actions at both testosterone level and signal transduction pathway in corpus cavernosum. NO/cGMP pathway appeared to play a key role in mediating the effect of Rg1 on male sexual function. These experimental data provide evidence that Rg1 could be a promising new drug for erectile dysfunction and low libido.