Antagonism at metabotropic glutamate 5 receptors inhibits nicotine- and cocaine-taking behaviours and prevents nicotine-triggered relapse to nicotine-seeking

Prefrontal cortical efferents in the rat synapse on unlabeled neuronal targets of catecholamine terminals in the nucleus accumbens septi and on dopamine neurons in the ventral tegmental area

Susan R. Sesack, Virginia M. Pickel · The Journal of Comparative Neurology · 1992 · 821 citations

Life Sciences, Neurobiology, Neuroscience +16

Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain

Carmelo Romano, Michael A. Sesma, Colin T. McDonald et al. · The Journal of Comparative Neurology · 1995 · 673 citations

Life Sciences, Neurobiology, Neuroscience +15

Repeated cocaine augments excitatory amino acid transmission in the nucleus accumbens only in rats having developed behavioral sensitization

R. Christopher Pierce, Ken Bell, Philip E. Duffy et al. · Journal of Neuroscience · 1996 · 621 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Glutamatergic Afferents from the Hippocampus to the Nucleus Accumbens Regulate Activity of Ventral Tegmental Area Dopamine Neurons

Stan Floresco, Christopher L. Todd, Anthony A. Grace · Journal of Neuroscience · 2001 · 560 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice

Cristiano Chiamulera, Mark P. Epping-Jordan, Alessandro Zocchi et al. · Nature Neuroscience · 2001 · 549 citations

Life Sciences, Neurobiology, Neuroscience +14