Publication | Open Access

Jak2 inhibition deactivates Lyn kinase through the SET–PP2A–SHP1 pathway, causing apoptosis in drug-resistant cells from chronic myelogenous leukemia patients

Hematological MalignancyReceptor Tyrosine KinaseApoptosisCancer Cell BiologyCell DeathJak2 InhibitionLyn KinaseDrug-resistant CellsRadiation OncologyMedicineCell BiologyCell SignalingCancer ResearchJak-stat Signaling PathwayMyeloid Neoplasia