Striking LD50 variation associated with fluctuations of CYP2E1-positive cells in hepatic lobule during chronic CCl4 exposure in mice

Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair

Jeremy S. Duffield, Stuart J. Forbes, Christothea M. Constandinou et al. · Journal of Clinical Investigation · 2005 · 1.4K citations · Full text

Medicine, Immunology, Pathology +17

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

F. Peter Guengerich, Dong‐Hyun Kim, M. Iwasaki · Chemical Research in Toxicology · 1991 · 1.2K citations

Medicine, Oncology, Toxicology +8

A morphologic study of deoxyribonucleic acid synthesis and cell proliferation in regenerating rat liver; autoradiography with thymidine-H3.

Joe W. Grisham · PubMed · 1962 · 771 citations

Life Sciences, Cell Biology, Cell Division +8

Glutathione-associated cis-diamminedichloroplatinum(II) metabolism and ATP-dependent efflux from leukemia cells. Molecular characterization of glutathione-platinum complex and its biological significance.

Toshihisa Ishikawa, Francis Ali‐Osman · Journal of Biological Chemistry · 1993 · 538 citations · Full text

Medicine, Biochemistry, Pharmacology +16

Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: Analysis of instances of therapeutic misadventure

Hyman J. Zimmerman, Willis C. Maddrey · Hepatology · 1995 · 449 citations

Pharmacy, Pharmacology, Toxicology +17