Journal of Burn Care & Rehabilitation · 1998 · 17 citations · 0 references
MedicinePerioperative MedicineSurgeryBurn SurgeryTransfusion MedicineWound HealingBlood Loss ManagementBlood PreservationBurn CareBurn ManagementCell SalvagePerioperative Blood ManagementAbdominal Trauma SurgeryBurn ExcisionIntraoperative Blood Loss AssessmentIntraoperative Blood Loss MeasurementIntraoperative Blood Loss ReductionIntraoperative Blood SalvageIntraoperative Cell SalvageWashed Blood Products
The diminution of intraoperative hemorrhage remains a fundamental goal of the burn surgeon. We hypothesized that intraoperative blood salvage during burn excisions would be feasible if predicated on yield, bacteriology, and concentration of inflammatory mediators in the washed product. Reinfusion of culture-positive blood has a clear precedent in the trauma literature. Eight operations with immediate and complete collection of shed blood into a cell-saver device were prospectively studied. A median salvage rate of 43% of total shed red blood cells was estimated to have been recovered. Actual volumetric measurement of intraoperative blood loss was achieved. Bacterial contamination was consonant with the abdominal trauma experience. The levels of C3a, C5a, TNF alpha, and IL-1 beta in the final cell-saver product were all found to be at clinically insignificant levels.