Concepedia

Publication | Closed Access

Assignment of the human skeletal muscle α-tropomyosin gene (TPM1) to band 15q22 by fluorescence in situ hybridization

DOI

20

Citations

0

References

1995

Year

H.J. Eyre, P. Anthony Akkari, Steve D. Wilton, D.C. Callen, Elizabeth Baker, Nigel G. Laing
Cytogenetic and Genome Research

Abstract

A sequence-tagged site (STS) was developed for the human skeletal muscle alpha-tropomyosin gene (TPM1) and used to isolate a genomic clone, lambda TPM1.1, containing part of the TPM1 gene. Fluorescence in situ hybridization of this clone to metaphase chromosome spreads localised TPM1 to chromosome band 15q22. This localisation in humans is consistent with that recently described for the mouse.