Phosphonate inhibitors of antigen 85C, a crucial enzyme involved in the biosynthesis of the Mycobacterium tuberculosis cell wall

Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function

Garrett M. Morris, David S. Goodsell, Robert S. Halliday et al. · Journal of Computational Chemistry · 1998 · 10.8K citations

Life Sciences, Bioinformatics, Molecular Biology +17

Distributed automated docking of flexible ligands to proteins: Parallel applications of AutoDock 2.4

Garrett M. Morris, David S. Goodsell, Ruth Huey et al. · Journal of Computer-Aided Molecular Design · 1996 · 1K citations

Life Sciences, Bioinformatics, Molecular Biology +15

Role of the Major Antigen of <i>Mycobacterium tuberculosis</i> in Cell Wall Biogenesis

John T. Belisle, Varalakshmi Vissa, Todd R. Sievert et al. · Science · 1997 · 727 citations

Life Sciences, Biochemistry, Molecular Biology +14

Inactivation of the antigen 85C gene profoundly affects the mycolate content and alters the permeability of the <i>Mycobacterium tuberculosis</i> cell envelope

Mary Jackson, Catherine Raynaud, Marie‐Antoinette Lanéelle et al. · Molecular Microbiology · 1999 · 258 citations

Life Sciences, Microbiology, Molecular Biology +13

Modeling the impact of global tuberculosis control strategies

Christopher J L Murray, Joshua A. Salomon · Proceedings of the National Academy of Sciences · 1998 · 242 citations

Public Health, Infectious Disease Control, Infectious Diseases +15