Dose-independent pharmacokinetics of digoxin in humans

An Algorithm for Least-Squares Estimation of Nonlinear Parameters

Donald W. Marquardt · Journal of the Society for Industrial and Applied Mathematics · 1963 · 30.4K citations

Natural Sciences, Computational Engineering, Optimization +11

Statistical estimations in pharmacokinetics

Harold Boxenbaum, Sidney Riegelman, Robert M. Elashoff · Journal of Pharmacokinetics and Biopharmaceutics · 1974 · 728 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +6

Determination of Therapeutic and Toxic Serum Digoxin Concentrations by Radioimmunoassay

Thomas W. Smith, Vincent P. Butler, Edgar Haber · New England Journal of Medicine · 1969 · 589 citations

Pharmacy, Pharmacology, Toxicology +9

Clinical Pharmacokinetics

David J. Greenblatt, Jan Koch‐Weser · New England Journal of Medicine · 1975 · 434 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +11

Assessment of Pharmacokinetic Constants from Postinfusion Blood Curves Obtained after I.V. Infusion

J.C.K. Loo, Sidney Riegelman · Journal of Pharmaceutical Sciences · 1970 · 302 citations

Pharmacy, Pharmacokinetics, Pharmacology +9