Concepedia

Publication | Open Access

Inhibition of Inflammatory Hyperalgesia by Activation of Peripheral CB2Cannabinoid Receptors

DOIFull Paper Access

236

Citations

0

References

2003

Year

Aline Quartilho, Heriberto P. Mata, Mohab Ibrahim, Todd W. Vanderah, Frank Porreca, Alexandros Makriyannis, T. Philip Malan
Anesthesiology

Abstract

Local, peripheral CB2 receptor activation inhibits inflammation and inflammatory hyperalgesia. These results suggest that peripheral CB2 receptors may be an appropriate target for eliciting relief of inflammatory pain without the CNS effects of nonselective cannabinoid receptor agonists.