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In aging, the vulnerability of rat brain mitochondria is enhanced due to reduced level of 2′,3′-cyclic nucleotide-3′-phosphodiesterase (CNP) and subsequently increased permeability transition in brain mitochondria in old animals

Neurodegenerative DiseasesAlzheimer's DiseaseAgingMitochondrial FunctionPermeability TransitionMitochondrial DynamicRat Brain MitochondriaPhysiologyBrain MitochondriaMitochondrial StructureDegenerative PathologyNeural AgingMitochondrial BiologyNeuroscienceBiogerontologyMedicineSocial SciencesOxidative Stress