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CONVERSION OF ANDROSTENEDIONE TO ESTRONE BY HUMAN FAT TISSUE
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References
1972
Year
PhysiologyPathologyGynecologyAverage ConversionAromataseEndocrinologyE1in VitroEndometrial CarcinomaMetabolismMedicineSteroid MetabolismCancer ResearchEndocrine-related CancerReproductive Endocrinology
The conversion of Δ4 to E1in vitro by human female fat tissue was investigated. In patients with endometrial carcinoma an average conversion of 0.1% was found. The values ranged from 0.03 to 0.19%. In the other patients this conversion was only 0.027 % with a range of 0.01 to 0.06 %. The significance of these results is discussed.