The Journal of Clinical Endocrinology & Metabolism · 1972 · 318 citations · 0 references
MedicineBiochemistryEndocrinologyHormone BiochemistryReproductive EndocrinologySteroid BiochemistryAndrogen PhysiologyEndometrial CancerAndrostenedione PhysiologyAromatization Of AndrogensEstrogen MetabolismEstrogen Metabolites
The conversion of Δ4 to E1in vitro by human female fat tissue was investigated. In patients with endometrial carcinoma an average conversion of 0.1% was found. The values ranged from 0.03 to 0.19%. In the other patients this conversion was only 0.027 % with a range of 0.01 to 0.06 %. The significance of these results is discussed.