Chemistry - A European Journal · 2004 · 89 citations · 70 references
Life SciencesMolecular BiologyDna RepairNucleic Acid BiochemistryStructural BiologyDna DamageDna StabilityDna Strand BreaksDna StructureNucleic Acid StructureRadiation ResistanceDna Adducts From Ultraviolet RadiationDna HairpinsPhotocleavage Of Nucleic AcidsRadiation-induced Dna DamageRna HairpinsUltraviolet Light TreatmentUltraviolet-induced Dna DamageUv-induced Dna Lesions
DNA and RNA hairpins, which represent well-folded oligonucleotide structures, were irradiated and the amount of damaged hairpins was directly quantified by using ion-exchange HPLC. The types of photoproducts formed in the hairpins were determined by ESI-HPLC-MS/MS experiments. Irradiation of hairpins with systematically varied sequences and conformations (A versus B) revealed remarkable differences regarding the amount of photolesions formed. UV-damage formation is, therefore, a strongly sequence and conformation dependent process.
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Walter Gilbert · Nature · 1986 · 2.7K citations · Full text
Crystal Structure of DNA Photolyase from <i>Escherichia coli</i>
Hee-Won Park, Sang‐Tae Kim, Aziz Sancar et al. · Science · 1995 · 577 citations