Role of prophylactic antibiotics in Milligan Morgan hemorrhoidectomy – A randomized control trial

Abstract

OBJECTIVE: Role of prophylactic antibiotics in Milligan Morgan hemorrhoidectomy - A prospective, randomized control trial. DESIGN: Randomized control trial. PLACE AND DURATION OF STUDY: Combined Military Hospital Malir, Bannu and HIT hospital Taxilla, September 2008 to February 2011. PATIENTS AND METHODS: Patients undergoing Milligan Morgan hemorrhoidectomy for grade III and IV hemorrhoids were randomized in 2 groups by using computer generated table. Group A did not receive any prophylactic antibiotic whereas group B received 500 mg I/V metronidazole and 1 g Ceftriaxone I/V before induction of anesthesia. All the patients had standardized post operative care. Pain scores on 100 mm Visual Analogue Scale and consumption of oral analgesics were noted from 1st to 7th post operative day. Time required for complete healing was also noted. Data was entered on SPSS 16.0 and p value was calculated. RESULTS: Out of 100 patients, 96 patients (47 in group A and 49 in group B) completed the study. Demographical data was comparable in both the groups. There was no difference in the pain scores, analgesic consumption and rate of healing between both the groups. CONCLUSION: Prophylactic antibiotics have got no role in cases of Milligan Morgan hemorrhoidectomy.