Genetic Engineering of Recombinant Hypoallergenic Oligomers of the Major Birch Pollen Allergen, Bet v 1: Candidates for Specific Immunotherapy

The gene coding for the major birch pollen allergen Betv1, is highly homologous to a pea disease resistance response gene.

Heimo Breiteneder, K. Pettenburger, A. Bito et al. · The EMBO Journal · 1989 · 678 citations · Full text

Life Sciences, Genetics, Plant Sciences +11

Identification of allergens in fruits and vegetables: IgE cross-reactivities with the important birch pollen allergens Bet v 1 and Bet v 2 (birch profilin)

C. Ebner, Reinhold Hirschwehr, Leonhardt Bauer et al. · Journal of Allergy and Clinical Immunology · 1995 · 408 citations

Life Sciences, Food Science, Immunology +15

IgE and IgG antibodies of patients with allergy to birch pollen as tools to define the allergen profile of <i>Betula verrucosa</i>*

Helmut Rumpold, Anne Endler, H Ebner et al. · Allergy · 1989 · 217 citations

Life Sciences, Immunology, Allergy +15

Conversion of the major birch pollen allergen, Bet v 1, into two nonanaphylactic T cell epitope-containing fragments: candidates for a novel form of specific immunotherapy.

Susanne Vrtala, Kora Hirtenlehner, Luca Vangelista et al. · Journal of Clinical Investigation · 1997 · 214 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Recombinant birch pollen allergens (rBet v 1 and rBet v 2) contain most of the IgE epitopes present in birch, alder, hornbeam, hazel, and oak pollen: A quantitative IgE inhibition study with sera from different populations

Verena Niederberger, G. Pauli, Hans Grönlund et al. · Journal of Allergy and Clinical Immunology · 1998 · 208 citations · Full text

Life Sciences, Immunology, Allergy +15