Annals of the New York Academy of Sciences · 2007 · 29 citations · 4 references
DentistryPeriodonticsPeriodontologyOral DiagnosisOral ImmunologyPeriodontal MedicineGingival DiseaseGingival InflammationOral Disease DiagnosticsPeriodontal DiseasePeriodontal ExaminationPeriodontal InflammationAutomated Enzyme-linked Immunosorbent AssayClinical Periodontal AssessmentGingival Crevicular Fluid BiomarkersGingival Crevicular Fluid SamplingGingivitis DiagnosisPeriodontal Disease DiagnosticsPeriodontal LesionsPeriodontitis Diagnosis
A novel immunology-based point-of-care test has been designed to assess the activated form of matrix metalloproteinase-8 (aMMP-8) for diagnosis and monitoring of periodontal diseases. The test has been automated using an analyzer, which quantitatively measures aMMP-8 in 18 min in gingival crevicular fluid (GCF). Fluid samples were collected from healthy, gingivitis-, and periodontitis-affected teeth. The test results from the analyzer were compared with quantitative aMMP-8 immunofluorometric assay (IFMA) and in-house enzyme-linked immunosorbent assay (ELISA) as well as with the periodontal state. Preliminary results of analyzer measurements of these 34 clinical samples showed a good agreement with the results from IFMA and in-house ELISA and with the clinical picture.
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Collagenases in Different Categories of Peri-implant Vertical Bone Loss
Jin Ma, Uula Kitti, Olli Teronen et al. · Journal of Dental Research · 2000 · 64 citations