THE PERMEABILITY OF LIVER AND SKIN CAPILLARIES TO LIPIDS IN THE CAT

Abstract

SUMMARY Lymph was collected from the hepatic and leg ducts of cats before and after the intravenous infusion of artificial fat emulsions, homologous chyle and heterologous hypercholesterolaemic plasma. The fat particles of the artificial fat emulsion appeared in the hepatic lymph in quantities similar to those previously found for chyle. In the paw there was only a very little transfer of the particles of artificial fat emulsion and chyle from plasma to lymph even after injuring the skin by a thermal burn. The smaller lipid complexes of hypercholesterolaemic rabbit plasma, however, penetrated the capillary membrane and appeared in the lymph. The mechanisms of transfer in the liver and in the skin have been discussed.