Cardiology · 2006 · 98 citations · 16 references
MedicineCardiologyPerioperative MedicineCardiovascular PharmacotherapyPerioperative PharmacologyPreventive CardiologyAtrial FibrillationPostoperative Cardiac CareThrombosis PreventionAtrial Fibrillation After Cardiac SurgeryKaplan-meier Confidence IntervalsKaplan-meier Survival EstimatesObservational Study AnalysisPerioperative Statin TherapyPostoperative Atrial Fibrillation
BACKGROUND: The aim of the present observational study is to search the incidence of postoperative atrial fibrillation (AF) in patients with or without preoperative statin treatment. METHODS AND RESULTS: The population consisted of 362 consecutive patients (267 on and 95 not on statin). Diabetes mellitus was more frequent in statin group (p = 0.03). Other demographic and procedural variables were similar in the both groups (All p > 0.05). Postoperative AF was less frequent and its duration was shorter in statin group compared to non-statin group (p = 0.03 and 0.0001, respectively). The Kaplan-Meier analysis showed the protective effect of statins against the risk of developing AF (p = 0.01). CONCLUSION: Statin treatment before the by-pass surgery decreases the incidence and shortens the duration of postoperative AF.
16
Scott M. Grundy · JAMA · 1993 · 27.9K citations
Inflammation as a Risk Factor for Atrial Fibrillation
Ronnier J. Aviles, David O. Martin, Carolyn Apperson-Hansen et al. · Circulation · 2003 · 1.4K citations
Histological Substrate of Atrial Biopsies in Patients With Lone Atrial Fibrillation
Andrea Frustaci, Cristina Chimenti, Fulvio Bellocci et al. · Circulation · 1997 · 1.4K citations
Medicine, Cardiology, Pathology +8
Predictors of Atrial Fibrillation After Coronary Artery Surgery
Sary F. Aranki, David P. Shaw, David Adams et al. · Circulation · 1996 · 1.2K citations
Medicine, Cardiology, Surgery +13