Neurosubstrates of Remission following Prolonged Exposure Therapy in Veterans with Posttraumatic Stress Disorder

Abstract

These findings suggest that the capacity to effectively remit from PTSD symptoms after PE treatment requires the ability to connect with physiological signals and moderate the discomfort of anticipatory anxiety of exposure therapy. These processes appear to be controlled by a network where the anterior insula is connected with the cingulate and the mid-posterior insula.