The Trehalase Inhibitor Salbostatin, a Novel Metabolite from <i>Streptomyces albus</i>, ATCC21838

Abstract

A new lead structure for the synthesis of trehalase inhibitors, salbostatin (1), is described. In one of the few systematic investigations into microorganism cultures, this pseudodisaccharide and a second metabolite 2 were isolated from the culture supernatant of a long-term fermentation. Trehalase inhibitors such as 1 are important compounds in the area of plant protection.