Concepedia

Influence of barrier-crossing limitations on the amount of macromolecular drug taken up by its target

Anne Aubrée-Lecat, Marie -Claude Duban, Sylvie Demignot, Martine Domurado, Philippe Fournié, Dominique Domurado

Journal of Pharmacokinetics and Biopharmaceutics · 1993 · 14 citations · 29 references

DOI

Concepts

References

29

The Theory of Tracer Experiments with <sup>131</sup>I-Labelled Plasma Proteins

C. M. E. Matthews · Physics in Medicine and Biology · 1957 · 834 citations

, , +14

Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: significance of elevated interstitial pressure.

R K Jain, Laurence T. Baxter · PubMed · 1988 · 715 citations

, , +17

Specific binding sites for albumin restricted to plasmalemmal vesicles of continuous capillary endothelium: receptor-mediated transcytosis.

Lucian Ghitescu, A Fixman, Maya Simionescu · The Journal of Cell Biology · 1986 · 371 citations · Full text

, , +13

Blood-brain barrier transcytosis of insulin in developing rabbits

Kent R. Duffy, William M. Pardridge · Brain Research · 1987 · 350 citations

, , +7

Modeling analysis of the global and microscopic distribution of immunoglobulin G, F(ab')2, and Fab in tumors.

Kenji Fujimori, David G. Covell, John Fletcher et al. · PubMed · 1989 · 261 citations

, , +17