Ln[N(SiMe₃)₂]₃‐Catalyzed Cross‐Diinsertion of CN/CC into an NH Bond: Facile Synthesis of 1,2,4‐Trisubstituted Imidazoles from Propargylamines and Nitriles

Abstract

A lanthanide-catalyzed sequential insertion of CN and CC into an NH bond is presented. The convenient reaction, which proceeds under mild conditions, is an efficient method for preparing 1,2,4-trisubstituted imidazoles directly from readily available propargylamines and nitriles.